Fig. 6. Lack of significant effects of siRNA-mediated knockdown of RhoG on high glucose-induced cell death in INS-1 832/13 cells. Following incubation with Low glucose (2.5 mM) and High glucose (20 mM) for 24 hours, cells were analyzed using Cell Death detection ELISA^plus kit. Absorbance was measured at 405nm and data are expressed as fold change relative to LG Mock (mean ± SEM; n=4; *p<0.05). Comparisons shown: a - significant compared with LG-treated mock; b - significant compared with LG-treated Cont-si.